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For the eight week period ending August 19, 2008, and based on sales at independent bookstores nationwide.
| 1. | The Host |
| 2. | 1984 |
| 3. | Ender's Game |
| 4. | Fahrenheit 451 |
| 5. | The Time Traveler's Wife |
| 6. | Wicked |
| 7. | Cat's Cradle |
| 8. | World War Z: An Oral History of the Zombie War |
| 9. | The Name of the Wind |
| 10. | Soon I Will Be Invincible |
| 11. | The Hobbit |
| 12. | Sandworms of Dune |
| 13. | Good Omens |
| 14. | Dune |
| 15. | Speaker for the Dead |
| 16. | The Dark River |
| 17. | Cry Wolf |
| 18. | The Lost World |
| 19. | A Game of Thrones |
| 20. | The Hitchhiker's Guide to the Galaxy |
| 21. | The Orc King |
| 22. | A Clash of Kings |
| 23. | The Once and Future King |
| 24. | A Clockwork Orange |
| 25. | Son of a Witch |